Ethinyl Estradiol, Norethisteron Therapeutic indications:

Hormone-dependent tumors (breast carcinoma or endometrium), acute or chronic liver diseases (including in history), deep vein thrombosis, thromboembolism, circulatory disorders (including in history), uterine bleeding of obscure etiology, hemoglobinopathy, porphyria.


Appointed with caution in hypertension, epilepsy, migraine, diabetes mellitus, bronchial asthma, heart failure (patients should be under medical supervision). Experience in treatment of women over 65 years of age is limited.

Pregnancy and lactation:

Contraindicated for pregnancy and lactation.

How to use and doses:

The pills are designed for continuous combined hormone replacement therapy in women with an unwanted uterus. The drug is taken orally 1 tablet a day without interruption, preferably at the same time of day.

In the treatment of symptoms of postmenopause, the drug should begin and resume at the lowest effective dose for short-term therapy.

If the response to therapy is insufficient, the transition to a higher-dose drug should be discussed after three months.

Patients with amenorrhoea who are not receiving hormone replacement therapy or are taking another combination drug on a continuous basis may start taking the tablets on any convenient day. When transferring patients from a cyclic regime of hormone replacement therapy, treatment should begin immediately after the end of menstrual bleeding caused by the drug withdrawal.

If you miss the next tablet, the missed pill should be taken as soon as possible within the next 12 hours. If the medication is more than 12 hours late, the missed tablet should be discarded. Missing another dose may cause uterine bleeding to break through or cause bleeding to appear. Dispose of unused medication according to local requirements.

Side effects:

In the first months of treatment: mammary gland pain, sporadic menstrual-like bleeding. Rarely - nausea, swelling, headache. If you continue treatment, these phenomena occur independently and do not require cancellation.


Overdose can cause nausea and vomiting.

Treatment: symptomatic.

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